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Analytical equipment and technology

  • Analytical HPLC and UHPLC (e.g. normal phase, RP-, ion pair chromatography), Ph.Eur.
    • isocratic, binary and trivalent high pressure gradient systems
    • column switching
    • cooling sample-compartment
  • DAD, UV/Vis-, RI and Fluorescence-detection
  • GC / MS equipped with headspace, Ph.Eur.
    • N2 and He as carrier gas
    • FID, MS-detection
  • Dissolution tester (e.g. paddle, basket, use of sinker), Ph.Eur.
  • Permeation testing by Franz-Cells
  • TLC, Ph.Eur.
  • Computer-controlled titration (Titrino, e.g. Karl Fischer), Ph.Eur.
  • UV/Vis-spectroscopy, Ph.Eur.
  • FTIR, Ph.Eur.
  • Gel chromatography (SEC), Ph.Eur.
  • Potentiometry, Ph.Eur.
  • Pharmaceutic-physical investigations (e.g. resistance to crushing, friability, disintegration, weight variation), Ph.Eur.
  • Loss on drying, Ph.Eur.
  • Determination of sub-visible particles by
    • Light obscureness, Ph.Eur. – Method 1
    • Microscope, Ph.Eur. – Method 2
  • Monitoring by light scattering (PCS) of nanoparticles and emulsions for parenteral application
  • Sieve analysis, Ph.Eur.
  • Bulk density / Tapped density, Ph.Eur.
  • Osmolarity, Ph.Eur.
  • Viscosity, Ph.Eur.
  • Melting point, Ph.Eur.
  • Optical rotation, Ph.Eur.
  • Refractometry, Ph.Eur.
  • Density Ph.Eur.
  • Biochemical methods, e.g. Electrophoresis technology, Western Blot, SEC